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Electronic (Non-injection) Mesotherapy

Ultra Cavi Sonic from RubicaThe demand for mesotherapy treatments has steadily risen in the recent years and it became one of the most common procedures in cosmetology, especially in Europe. However, despite the high number of treatments conducted every year and the continual refinement of injection technologies, the method is not perfect. The chief problem is patient discomfort during the procedure, as well as traces left by the injections. Occasionally, there may even be complications such as hematomas.

Principles of Electronic Mesotherapy

Electronic mesotherapy is a completely new approach, still called mesotherapy only because it strives to fill the same niche and its treatments serve the same purposes. In reality it has very little in common with traditional mesotherapy injections because electronic mesotherapy allows for delivery of medications into the skin without a needle and, consequently, without breaking the integrity of the skin’s surface. Electronic mesotherapy treatments are conducted absolutely without pain or unpleasant sensations, and have no potential side effects (other than possible allergic reactions to the durg itself).


Non-injection mesotherapyMechanism of Action

Electronic mesotherapy is based upon the phenomenon of electroporation – a way to transport substances transepidermally using high voltage pulse current. The current temporarily destabilizes lipid bilayers of cells, allowing water-soluble drugs to permeate through the stratum corneum (hardened top layer of the skin). These channels exist a short time immediately following an electric pulse and close afterwards. Intercellular spaces that are created using the method of electroporation adapt their diameter to the size of molecules passing through them.  

Efficiency of electroporation has been verified in numerous scientific studies. The appearance of transport channels has been documented using electron microscopy. Molecules of any size can be delivered into the dermis using electroporation and the depth of permeation can be controlled as well as with any injector. Just like in traditional mesotherapy, a cosmetologist can use any of the aqueous solutions, called mesotherapeutic cocktails, to address specific problems of each patient.